The Vikings have 6 days' rest since Sunday's game in Green Bay, with 2,984 km (1,854 miles) of travel.
The 49ers have 6 days' rest since Sunday's game in Arlington, with 1,509 km (938 miles) of travel, playing 2 hours ahead of their home clock.
Conference game outdoors at a neutral site in Mexico City, Mexico; at altitude (2,287 m); broadcast on NBC.
NFL teams after 2,000 km or more of travel have won 50% of regular-season games since 2015 (1,528 team-games).
From the published schedule, computed 6 Sep 2026. No odds or predictions. All NFL games this week
Last updated
The Minnesota Vikings face the San Francisco 49ers in the 2026 NFL regular season on Sunday 22 November 2026 at Estadio Banorte, Mexico City.
Kick-off is 8:20 PM ET. NFL games are shown in the United States across CBS, FOX, NBC, ESPN/ABC and Amazon Prime Video depending on the slot, and internationally on Sky Sports and DAZN. Confirmed broadcast details are listed nearer kick-off.